Donald J Davidson Selected Research

Antimicrobial Cationic Peptides

3/2016	Cathelicidins Have Direct Antiviral Activity against Respiratory Syncytial Virus In Vitro and Protective Function In Vivo in Mice and Humans.
1/2011	Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37.
12/2010	The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium.
3/2009	The host defense peptide LL-37 selectively permeabilizes apoptotic leukocytes.
4/2006	Apoptosis of airway epithelial cells: human serum sensitive induction by the cathelicidin LL-37.
4/2005	Impact of LL-37 on anti-infective immunity.

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Donald J Davidson Research Topics

Disease

20	Infections 09/2021 - 04/2004
16	Inflammation (Inflammations) 01/2021 - 01/2004
3	Virus Diseases (Viral Diseases) 01/2020 - 01/2014
3	Neoplasms (Cancer) 01/2019 - 04/2005
3	Bronchiectasis 10/2018 - 06/2014
3	Necrosis 01/2014 - 08/2009
2	Communicable Diseases (Infectious Diseases) 01/2020 - 09/2006
2	Premature Birth (Birth, Premature) 01/2019 - 01/2018
2	Pneumonia (Pneumonitis) 10/2018 - 08/2013
2	Cough 01/2017 - 06/2014
2	Critical Illness (Critically Ill) 05/2011 - 07/2009
2	Chronic Disease (Chronic Diseases) 10/2009 - 03/2007
2	Pneumococcal Infections 03/2007 - 04/2004
1	Cystic Fibrosis (Mucoviscidosis) 01/2021
1	Pre-Eclampsia (Preeclampsia) 01/2020
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2019
1	Wounds and Injuries (Trauma) 10/2018
1	Pregnancy Complications 01/2018
1	Premature Obstetric Labor (Premature Labor) 01/2018
1	Bites and Stings (Sting) 01/2018
1	Respiratory Syncytial Virus Infections 03/2016
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2015
1	Autoimmune Diseases (Autoimmune Disease) 12/2015
1	Bacterial Infections (Bacterial Infection) 01/2015
1	Neonatal Sepsis 01/2015
1	Pseudomonas Infections 01/2014
1	Acute Lung Injury 09/2012
1	Lung Injury 09/2012
1	Cross Infection (Nosocomial Infection) 05/2011
1	Human Influenza (Influenza) 01/2011
1	Ventilator-Associated Pneumonia 03/2010
1	Peritonitis 08/2009
1	Glioblastoma (Glioblastoma Multiforme) 07/2009
1	Brain Neoplasms (Brain Tumor) 07/2009
1	IRAK4 Deficiency 12/2006
1	Carcinoma (Carcinomatosis) 04/2005
1	Neoplasm Metastasis (Metastasis) 04/2005
1	Melanoma (Melanoma, Malignant) 04/2005
1	Lewis Lung Carcinoma 04/2005
1	Salmonella Infections (Salmonellosis) 04/2005

Drug/Important Bio-Agent (IBA)

12	Peptides (Polypeptides)IBA 01/2020 - 02/2005
11	CathelicidinsIBA 01/2021 - 01/2004
6	Antimicrobial Cationic PeptidesIBA 03/2016 - 04/2005
5	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 01/2014
5	DefensinsIBA 01/2020 - 01/2011
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 07/2009
4	LipopolysaccharidesIBA 01/2020 - 09/2012
4	Antimicrobial PeptidesIBA 01/2020 - 01/2011
4	Antiviral Agents (Antivirals)IBA 10/2017 - 01/2011
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 09/2006
3	CytokinesIBA 08/2013 - 04/2004
3	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2010 - 04/2004
2	RNA (Ribonucleic Acid)IBA 01/2019 - 03/2014
2	InterferonsIBA 01/2018 - 10/2017
2	Atorvastatin (Lipitor)FDA Link 01/2017 - 06/2014
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 06/2014
2	NF-kappa B (NF-kB)IBA 12/2006 - 04/2004
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2021
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2019
1	InflammasomesIBA 01/2019
1	CaspasesIBA 01/2019
1	Type III Secretion SystemsIBA 01/2019
1	Peroxidase (Myeloperoxidase)IBA 10/2018
1	LigandsIBA 10/2018
1	Acetylmuramyl-Alanyl-IsoglutamineIBA 10/2018
1	Cell-Free Nucleic AcidsIBA 01/2018
1	Toll-Like Receptor 9IBA 01/2018
1	Interferon Type IIBA 10/2017
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2017
1	VaccinesIBA 01/2017
1	Pattern Recognition ReceptorsIBA 03/2014
1	Pathogen-Associated Molecular Pattern MoleculesIBA 03/2014
1	Peptidoglycan (Murein)IBA 01/2014
1	lipoteichoic acidIBA 01/2014
1	phytobacteriomycin (PBM)IBA 09/2012
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 05/2011
1	Interleukin-1beta (Interleukin 1 beta)IBA 03/2010
1	Interleukin-8 (Interleukin 8)IBA 03/2010
1	alpha-DefensinsIBA 08/2009
1	Endoplasmic Reticulum Chaperone BiPIBA 07/2009
1	Complement System Proteins (Complement)IBA 07/2009
1	Purinergic P2X7 ReceptorsIBA 03/2007
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 12/2006
1	Biological ProductsIBA 04/2005
1	NAc- Sar- Gly- Val- (d- allo- Ile)- Thr- Nva- Ile- Arg- ProNEt (ABT 510)IBA 04/2005
1	matrigelIBA 04/2005
1	Culture MediaIBA 04/2005
1	Interleukin Receptors (Interleukin Receptor)IBA 04/2004
1	Phosphotransferases (Kinase)IBA 04/2004

Therapy/Procedure

9	Therapeutics 01/2020 - 09/2006
1	Operative Surgical Procedures 09/2021
1	Debridement 09/2021
1	Aftercare (After-Treatment) 10/2018